interrogans serovar Canicola is one of the most important pathogenic leptospires and, although it is considered highly adapted to dogs ( Schuller et al. already discussed the existence of variation of maintenance hosts and their respective serovars.
Nevertheless, Hartskeerl and Terpstra (1996) Hartskeerl RA, Terpstra WJ. interrogans serovars present importance for maintenance of urban leptospirosis and are described as adapted to biased reservoir hosts, such as serovar Copenhageni and rodents and serovar Canicola and dogs ( Bolin 2000 Bolin C. Distribution of plasmids in distinct Leptospira pathogenic species. 2015 Wang Y, Zhuang X, Zhong Y, Zhang C, Zhang Y, Zeng L, et al. Leptospira interrogans is the most frequently reported species worldwide and of greater importance for public health ( Haake & Levett 2015 Haake DA, Levett PN. Human leptospirosis: an emerging risk in Europe? Comp Immun Microbiol Infect Dis. 2014 Dupouey J, Faucher B, Edouard S, Richeta H, Kodjo A, Drancourt M, et al. Leptospirosis is a re-emerging zoonosis in both developed and developing countries ( Dupouey et al. interrogans serovar Canicola genomics plasmid The plasmids identification in the Brazilian and Chinese serovar Canicola strains suggest that extra-chromosomal elements are one more feature of this serovar that was previously unnoticed. Both human and porcine serovar Canicola isolates also presented sequences with high identity to the Chinese serovar Canicola published plasmids pGui1 and pGui2.
It was observed that the porcine serovar Canicola strains present the genetic machinery to cause human infection and, therefore, represent a higher risk to public health. interrogans serovar Canicola strains isolated from slaughtered sows (L0-3 and L0-4) and their comparison with human strain Fiocruz LV133. Here, we present the genomic characterisation of two Brazilian L. Even though it is considered highly adapted to dogs, serovar Canicola infection has already been described in other animals and even a few human cases. Leptospira interrogans serovar Canicola is one of the most important pathogenic serovars for the maintenance of urban leptospirosis.
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